Health Information

March 2013 Briefing - Family Practice

March 2013 Briefing - Family Practice

Reassortment of Flu Viruses Most Likely in China, Nile Delta

FRIDAY, March 29 (HealthDay News) -- The potential for reassortment between human and avian influenza viruses underscores that emerging diseases arise at the convergence of the human and animal domains, according to a study published in the April issue of Emerging Infectious Diseases.

Full Text (http://wwwnc.cdc.gov/eid/article/19/4/12-0903_article.htm )

Multiple Strategies Are More Efficient for Cervical Cancer

FRIDAY, March 29 (HealthDay News) -- Multiple cervical cancer screening strategies that maximize early detection of high-grade disease without excessive increases in initial testing appear to be most effective, according to a study published in the March issue of the American Journal of Obstetrics & Gynecology.

Abstract (http://www.ajog.org/article/S0002-9378(12)02075-3/abstract )Full Text (subscription or payment may be required) (http://www.ajog.org/article/S0002-9378(12)02075-3/fulltext )

Sex, Age at Presentation Affect Cirrhosis Response to Therapy

FRIDAY, March 29 (HealthDay News) -- Among patients with primary biliary cirrhosis (PBC), sex and age at presentation affect the response to ursodeoxycholic acid (UDCA), according to a study published in the March issue of Gastroenterology.

Abstract (http://www.gastrojournal.org/article/S0016-5085%2812%2901791-X/abstract )Full Text (http://www.gastrojournal.org/article/S0016-5085(12)01791-X/fulltext )

Hormone Therapy Ups Breast Cancer Risk, Mortality

FRIDAY, March 29 (HealthDay News) -- Postmenopausal hormone therapy with estrogen plus progestin is associated with an increased risk of breast cancer, according to a study published online March 29 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt043.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt043.full )Editorial (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt058.extract )

Computer-Based Programs Show Benefits for Diabetes

FRIDAY, March 29 (HealthDay News) -- Computer-based diabetes self-management interventions have a small beneficial effect on blood glucose control, according to a review published online March 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008776.pub2/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008776.pub2/full )

Genetic Profiles Linked to Progression to Heavy Smoking

FRIDAY, March 29 (HealthDay News) -- Individuals with genetic profiles putting them at risk of greater smoking are more likely to progress to heavy smoking and nicotine dependence, particularly if they quickly became daily smokers and heavy smokers as adolescents, according to a study published online March 27 in JAMA Psychiatry.

Abstract (http://archpsyc.jamanetwork.com/article.aspx?articleid=1672838#Abstract )Full Text (subscription or payment may be required) (http://archpsyc.jamanetwork.com/article.aspx?articleid=1672838 )

Higher Activity Levels May Protect Children From Stress

FRIDAY, March 29 (HealthDay News) -- Children with lower levels of daytime physical activity (PA) have higher hypothalamic-pituitary-adrenocortical axis (HPAA) activity in response to psychosocial stress, suggesting that PA may help children cope with stressful situations, according to research published online March 7 in the Journal of Clinical Endocrinology & Metabolism.

Abstract (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-3745.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-3745.full.pdf+html )

Many Uninsured Vets Will Be Eligible for Medicaid Under ACA

FRIDAY, March 29 (HealthDay News) -- A large proportion of uninsured veterans and their spouses will be eligible for Medicaid or new subsidies for coverage under the Affordable Care Act (ACA), according to a report published by the Robert Wood Johnson Foundation.

More Information (http://www.rwjf.org/content/dam/farm/reports/issue_briefs/2013/rwjf405143 )

Greater Vaccine Exposure Not Tied to Increased Autism Risk

FRIDAY, March 29 (HealthDay News) -- Increased exposure to vaccines during the first two years of life is not associated with an increased risk of autism, according to a study published online March 29 in The Journal of Pediatrics.

Full Text (http://www.jpeds.com/webfiles/images/journals/ympd/JPEDSDeStefano.pdf )

Gastric Bypass Leads to Gut Microbiota Changes in Mice

FRIDAY, March 29 (HealthDay News) -- Mice that undergo gastric bypass surgery have changes in their gut composition independent of weight loss, and transferring the gut microbiota to germ-free mice results in weight loss without sugery, according to a study published in the March 27 issue of Science Translational Medicine.

Abstract (http://stm.sciencemag.org/content/5/178/178ra41 )Full Text (subscription or payment may be required) (http://stm.sciencemag.org/content/5/178/178ra41.full )

Metabolite-Based Test May Detect Early Pancreatic Cancer

FRIDAY, March 29 (HealthDay News) -- A test that measures four serum metabolites can accurately distinguish patients with pancreatic cancer from healthy people and patients with pancreatitis, according to a study published online March 29 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract (http://cebp.aacrjournals.org/content/early/2013/03/27/1055-9965.EPI-12-1033.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/early/2013/03/27/1055-9965.EPI-12-1033.full.pdf+html )

Study Examines Physician Prescription of Teen IUDs

FRIDAY, March 29 (HealthDay News) -- Primary care physicians are more or less likely to prescribe long-acting reversible contraception such as intrauterine devices (IUDs) to adolescents based on their knowledge, skills, clinical environment, and attitudes, according to research published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/130.abstract )Full Text (http://www.annfammed.org/content/11/2/130.full )

Low Vitamin D Levels Common Among Spinal Fusion Patients

THURSDAY, March 28 (HealthDay News) -- A substantially high number of patients undergoing spinal fusion have a vitamin D deficiency or inadequacy, according to a study published in the March 15 issue of Spine.

Abstract (http://journals.lww.com/spinejournal/Abstract/2013/03150/Preoperative_Vitamin_D_Status_of_Adults_Undergoing.10.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/spinejournal/Abstract/2013/03150/Preoperative_Vitamin_D_Status_of_Adults_Undergoing.10.aspx )

Viral DNA-Based Testing Can Triage Women With Abnormal Pap

THURSDAY, March 28 (HealthDay News) -- DNA-based testing with Hybrid Capture 2 (HC2) assay is more accurate than repeat cytology in identifying women with cervical cancer when their initial Pap smear shows atypical squamous cells of undetermined significance (ASCUS), according to research published online March 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008054.pub2/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008054.pub2/full )

Pre-College Talk With Parents Reduces Student Drinking

THURSDAY, March 28 (HealthDay News) -- Parents talking to their matriculating college-age students about drinking lessens alcohol consumption, according to a study published in the January issue of the Journal of Studies on Alcohol and Drugs.

Abstract (http://www.jsad.com/jsad/article/Evaluation_of_Timing_and_Dosage_of_a_ParentBased_Intervention_to_Minimize_/4771.html )Full Text (subscription or payment may be required) (http://www.jsad.com/jsad/login&src=article,forward,4771 )

Higher Fiber Intake Tied to Lower Risk of First Stroke

THURSDAY, March 28 (HealthDay News) -- Higher fiber intake is associated with a lower risk of first stroke, according to a meta-analysis published online March 28 in Stroke.

Abstract (http://stroke.ahajournals.org/content/early/2013/03/27/STROKEAHA.111.000151.abstract )Full Text (subscription or payment may be required) (http://stroke.ahajournals.org/content/early/2013/03/27/STROKEAHA.111.000151.full.pdf+html )

Regional Variation Noted in Prevalence of Delayed Care

THURSDAY, March 28 (HealthDay News) -- There is considerable county-wide variation in the prevalence of delayed care, with high prevalence linked to a weaker health care infrastructure, according to a letter published in the March 28 issue of the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMc1214874 )

Birth Weight, Early Linear Growth Rate Affect Later Health

THURSDAY, March 28 (HealthDay News) -- In low- and middle-income countries, fast linear growth in the first two years of life is associated with increased adult height and completion of more schooling, while higher weight at birth and later in childhood is associated with increased risk of obesity, according to a study published online March 28 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60103-8/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60103-8/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60716-3/fulltext )

Breath Test Ties Hydrogen, Methane to Higher BMI

THURSDAY, March 28 (HealthDay News) -- There is a significant association between having both high methane and hydrogen results on a breath test and having a higher body mass index (BMI), according to a study published online March 26 in the Journal of Clinical Endocrinology & Metabolism.

Abstract (http://jcem.endojournals.org/content/early/2013/03/22/jc.2012-3144.abstract?sid=ef0f0d6a-79f7-4316-9fb9-bdfffc20a879 )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/03/22/jc.2012-3144.full.pdf+html )

Academic Urology Training Program in Crisis

THURSDAY, March 28 (HealthDay News) -- The current system of Graduate Medical Education (GME) funding is not adequate in funding urology residency programs and may lead to a significant shortage of urologists in the United States, according to research published in the March issue of Urology.

Abstract (http://www.goldjournal.net/article/S0090-4295(12)01476-8/abstract )Full Text (subscription or payment may be required) (http://www.goldjournal.net/article/S0090-4295(12)01476-8/fulltext )

H. pylori Status May Affect Recurrent Ulcer Bleeding

THURSDAY, March 28 (HealthDay News) -- Risk of recurrent ulcer bleeding is low in long-term low-dose aspirin (ASA) users with a history of ulcer bleeding and eradication of Helicobacter pylori (H. pylori), but high in ASA users with a history of ulcer bleeding and negative for H. pylori, according to research published in the March issue of Gastroenterology.

Abstract (http://www.gastrojournal.org/article/S0016-5085(13)00072-3/abstract )Full Text (http://www.gastrojournal.org/article/S0016-5085(13)00072-3/fulltext )

Study: Primary Care Extension Program Should Be Funded

THURSDAY, March 28 (HealthDay News) -- The Primary Care Extension Program (PCEP) has the potential to transform primary care and needs to be funded, according to a study published in the March/April issue of the Annals of Family Medicine.

Abstract (http://annfammed.org/content/11/2/173.abstract )Full Text (subscription or payment may be required) (http://annfammed.org/content/11/2/173.full )

Cell-Cycle Progression Panel Identifies Prostate Cancer Risk

THURSDAY, March 28 (HealthDay News) -- The cell-cycle progression (CCP) gene panel is useful to improve the risk stratification for men with even low-risk, clinically localized prostate cancer, according to research published online March 4 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.46.4396.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.46.4396.full.pdf+html )

Using Internet Search Logs Can Help Identify Drug Interactions

THURSDAY, March 28 (HealthDay News) -- Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

Abstract (http://jamia.bmj.com/content/early/2013/02/05/amiajnl-2012-001482.abstract )Full Text (subscription or payment may be required) (http://jamia.bmj.com/content/early/2013/02/05/amiajnl-2012-001482.full.pdf+html )

Texts Do Not Promote Flu Vaccination During Pregnancy

WEDNESDAY, March 27 (HealthDay News) -- Text messages encouraging pregnant women to get an influenza vaccination are ineffective, according to a study published in the April issue of Obstetrics & Gynecology. A related study in the same journal examines factors predicting influenza vaccination among pregnant women.

Abstract - Henninger (http://journals.lww.com/greenjournal/Abstract/2013/04000/Predictors_of_Seasonal_Influenza_Vaccination.8.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/2013/04000/Predictors_of_Seasonal_Influenza_Vaccination.8.aspx )Abstract - Moniz (http://journals.lww.com/greenjournal/Abstract/2013/04000/Improving_Influenza_Vaccination_Rates_in_Pregnancy.7.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/2013/04000/Improving_Influenza_Vaccination_Rates_in_Pregnancy.7.aspx )

Genetic Variant Boosts Asthma Risk in Children With HRV

WEDNESDAY, March 27 (HealthDay News) -- The 17q21 genotype increases the risk of asthma in children who have had human rhinovirus (HRV) wheezing illness, according to a study published online March 27 in the New England Journal of Medicine.

Abstract (http://www.nejm.org/doi/full/10.1056/NEJMoa1211592?query=featured_home )Full Text (http://www.nejm.org/doi/full/10.1056/NEJMoa1211592?query=featured_home#t=article )

Trial Shows Miravirsen Decreases HCV RNA Levels

WEDNESDAY, March 27 (HealthDay News) -- Subcutaneous injections of miravirsen, an miRNA inhibitor, result in significant virologic responses in patients with chronic hepatitis C virus (HCV) infection, according to a study published online March 27 in the New England Journal of Medicine.

Abstract (http://www.nejm.org/doi/full/10.1056/NEJMoa1209026?query=featured_home )Full Text (http://www.nejm.org/doi/full/10.1056/NEJMoa1209026?query=featured_home#t=article )Editorial (http://www.nejm.org/doi/full/10.1056/NEJMe1301348?query=featured_home )

Management of Short Stature in Childhood Discussed

WEDNESDAY, March 27 (HealthDay News) -- Short stature in childhood warrants evaluation, and various treatment options should be considered, according to a case vignette published in the March 28 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMcp1213178 )

Inpatient Deaths Fell by 8 Percent in Last Decade

WEDNESDAY, March 27 (HealthDay News) -- The number of inpatient hospital deaths declined by 8 percent over the last decade, although the total number of hospitalizations increased by 11 percent during the same period, according to a March data brief issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

Full Text (http://www.cdc.gov/nchs/data/databriefs/db118.htm )

Psoriasis Tied to Increased Risk of New-Onset Diabetes

WEDNESDAY, March 27 (HealthDay News) -- Psoriasis is significantly tied to an increased risk of new-onset diabetes mellitus (DM), according to a study published online March 14 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/03/10/dc12-2330.abstract?sid=b4448a37-58bc-47c5-be9e-45a2a7781dcb )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/03/10/dc12-2330.full.pdf+html )

Submitting Peer-Review Reports Could Expedite Process

WEDNESDAY, March 27 (HealthDay News) -- Attaching previous peer-review reports during the next submission of the same paper to a different journal could optimize the peer-review process, according to research published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/179.abstract?sid=830532ac-da58-4c89-87ca-b0c3ee2f8ffc )Full Text (http://www.annfammed.org/content/11/2/179.full )Editorial (http://www.annfammed.org/content/11/2/104.full?sid=48707c4b-ebf8-4a86-b8b0-726cf918c1ed )

Novel Approach Found for Treating Hypertrophic Scars

WEDNESDAY, March 27 (HealthDay News) -- Same-session therapy with fractional ablative laser treatment followed immediately with topical application of triamcinolone acetonide suspension is effective in treating patients with hypertrophic and restrictive cutaneous scars, according to research published in the March issue of Lasers in Surgery and Medicine.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/lsm.22120/abstract )Full Text (http://onlinelibrary.wiley.com/doi/10.1002/lsm.22120/full )

Daylight Savings Time Modestly Affects AMI Type, Incidence

WEDNESDAY, March 27 (HealthDay News) -- Transition to and from daylight savings time (DST) might modestly affect the incidence and type of acute myocardial infarction (AMI), according to research published in the March issue of The American Journal of Cardiology.

Abstract (http://www.ajconline.org/article/S0002-9149(12)02443-5/abstract )Full Text (subscription or payment may be required) (http://www.ajconline.org/article/S0002-9149(12)02443-5/fulltext )

Weight Loss, Muscle Depletion May Predict Cancer Survival

WEDNESDAY, March 27 (HealthDay News) -- Cancer patients with high weight loss, low muscle index, and low muscle attenuation have a poor prognosis regardless of body mass index (BMI), according to a study published online March 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.45.2722.abstract?sid=7d429274-7dd2-4e6f-b20e-fcb3ae02af94 )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.45.2722.full.pdf+html?sid=da40cfa2-827f-416e-b931-5e9aceb76ffc )

Smoking Has Gender-Specific Effect in Urothelial Carcinoma

WEDNESDAY, March 27 (HealthDay News) -- For patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU), the impact of smoking is gender specific, with worse outcomes for females than for males, according to a study published online March 6 in BJU International.

Abstract (http://onlinelibrary.wiley.com/doi/10.1111/bju.12014/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/bju.12014/full )

MRI Detects Cortical Brain Abnormalities for Migraines

WEDNESDAY, March 27 (HealthDay News) -- Patients with migraines have cortical thickness and surface area abnormalities that may represent both a predisposition to the condition as well as disease-related processes, according to a study published online March 26 in Radiology.

Abstract (http://radiology.rsna.org/content/early/2013/03/13/radiol.13122004.abstract )Full Text (subscription or payment may be required) (http://radiology.rsna.org/content/early/2013/03/13/radiol.13122004.full )

Mild Impairment at Diagnosis of Parkinson's Ups Dementia Risk

WEDNESDAY, March 27 (HealthDay News) -- Mild cognitive impairment (MCI) at the time of a diagnosis of Parkinson's disease (PD) predicts a highly increased risk for early dementia, according to a study published online March 25 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1671737#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1671737 )Editorial (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1671738 )

Majority of Lumbar Spine MRIs Are Inappropriately Ordered

WEDNESDAY, March 27 (HealthDay News) -- There is substantial overuse of lumbar magnetic resonance imaging (MRI) scans, according to a research letter published online March 25 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1672286 )

Early Baldness Ups Prostate CA Risk for African-Americans

TUESDAY, March 26 (HealthDay News) -- For African-Americans, who are at elevated prostate cancer risk, baldness at age 30 correlates with prostate cancer, with frontal baldness linked to increased odds of high-stage and high-grade disease, according to a study published online March 26 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.full.pdf+html )

Chelation Therapy Effectiveness Is Limited After Heart Attack

TUESDAY, March 26 (HealthDay News) -- Chelation therapy only results in a small reduction of the risk of a cardiovascular event following a myocardial infarction (MI) and should not be used in routine clinical care, according to a study published in the March 27 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1672238#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672238 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672219 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672221 )

Macrolide Antibiotics Are Effective for Bronchiectasis

TUESDAY, March 26 (HealthDay News) -- Macrolide antibiotics are effective in reducing exacerbations in patients with non-cystic fibrosis bronchiectasis, although the resistance rate increases, according to two studies published in the March 27 issue of the Journal of the American Medical Association.

Abstract - Altenburg (http://jama.jamanetwork.com/article.aspx?articleid=1672237#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672237 )Abstract - Serisier (http://jama.jamanetwork.com/article.aspx?articleid=1672240#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672240 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672222 )

Certified Primary Stroke Centers Use More Rt-PA

TUESDAY, March 26 (HealthDay News) -- Joint Commission certified primary stroke centers (PSCs) use more recombinant tissue plasminogen activator (rt-PA) for ischemic stroke than non-PSCs, according to a study published online March 26 in the Journal of the American Heart Association.

Abstract (http://jaha.ahajournals.org/content/2/2/e000071.abstract )Full Text (http://jaha.ahajournals.org/content/2/2/e000071.full )

Sublingual Immunotherapy Effective for Allergies

TUESDAY, March 26 (HealthDay News) -- Current studies show moderate evidence that sublingual immunotherapy is effective for allergic rhinitis, although the optimal dosing is unclear, according to a review published in the March 27 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1672214#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672214 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1672220 )

Supplement Aids Age-Related Macular Degeneration

TUESDAY, March 26 (HealthDay News) -- A supplement containing a combination of lutein, zeaxanthin, and ω-3 long-chain polyunsaturated fatty acids (LC-PUFAs) significantly benefits patients with age-related macular degeneration (AMD), according to a study published online March 21 in JAMA Ophthalmology.

Abstract (http://archopht.jamanetwork.com/article.aspx?articleid=1671044#Abstract )Full Text (subscription or payment may be required) (http://archopht.jamanetwork.com/article.aspx?articleid=1671044 )

Residency Reforms Reduced Duty Hours, Increased Sleep

TUESDAY, March 26 (HealthDay News) -- Additional residency reforms implemented in 2011 have reduced duty hours and increased sleep duration, but with perceived reductions in quality of patient care, according to research published online March 25 in JAMA Internal Medicine.

Abstract - Sen (http://archinte.jamanetwork.com/article.aspx?articleid=1672284#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1672284 )Abstract - Desai (http://archinte.jamanetwork.com/article.aspx?articleid=1672279#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1672279 )

Social Isolation, Apart From Loneliness, Can Harm Health

TUESDAY, March 26 (HealthDay News) -- Both loneliness and social isolation are associated with mortality, with the link for social isolation independent of demographics, baseline health, and loneliness, according to a study published online March 25 in the Proceedings of the National Academy of Sciences.

Abstract (http://www.pnas.org/content/early/2013/03/19/1219686110.abstract )Full Text (http://www.pnas.org/content/early/2013/03/19/1219686110.full.pdf+html )

Risk of Prostate Cancer Quantified for Lynch Syndrome

TUESDAY, March 26 (HealthDay News) -- Lynch syndrome carriers have about a two-fold increased risk of prostate cancer, according to a study published online March 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.44.1238.abstract )Full Text (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.44.1238.full.pdf+html )

MRSA Colonization in Groin Tied to Clinical Infections

TUESDAY, March 26 (HealthDay News) -- Groin colonization of methicillin-resistant Staphylococcus aureus (MRSA) leads to an increased risk of developing active MRSA infection later among HIV-infected patients, according to a study published in the April issue of Emerging Infectious Diseases.

Full Text (http://wwwnc.cdc.gov/eid/article/19/4/12-1353_article.htm )

Sleep Duration Affects Glycemic Control in Type 2 Diabetes

TUESDAY, March 26 (HealthDay News) -- Patients with type 2 diabetes with either a short or long sleep duration have significantly higher hemoglobin A1c (A1C) levels compared to patients with intermediate sleep duration, according to research published in the March issue of Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/36/3/611.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/36/3/611.full )

One in 10 Parents Often Don't Follow Pediatricians' Advice

TUESDAY, March 26 (HealthDay News) -- Although the majority of parents follow the advice of their child's health care provider most or all of the time, a considerable percentage of parents only occasionally follow their advice, according to a report published March 18 by the C.S. Mott Children's Hospital.

More Information (http://mottnpch.org/reports-surveys/just-what-doctor-ordered-not-many-parents )

Age of Menarche, Menopause Linked to Cardiovascular Risk

TUESDAY, March 26 (HealthDay News) -- For Chinese women, the age of menarche and menopause is not related to the risk of diabetes, but does correlate with cardiovascular disease and osteoporosis, according to a study published online March 7 in the Journal of Clinical Endocrinology & Metabolism.

Abstract (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-2919.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-2919.long )

Unintended Harmful Effects of Mammography Studied

TUESDAY, March 26 (HealthDay News) -- A false-positive test result from screening mammography is not harmless and can result in negative long-term psychosocial consequences, according to research published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/106.abstract )Full Text (http://www.annfammed.org/content/11/2/106.full )

HCV Transmission Risk Is Low in Monogamous Couples

MONDAY, March 25 (HealthDay News) -- Monogamous heterosexual couples where one partner is infected with hepatitis C virus (HCV) are at very low risk of transmitting the virus to the uninfected partner, according to a study in the March issue of Hepatology. A related study in the same journal found that the prevalence of HCV infection among newly incarcerated inmates is about 1 percent.

Abstract - Kim (http://onlinelibrary.wiley.com/doi/10.1002/hep.26113/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/hep.26113/full )Abstract - Terrault (http://onlinelibrary.wiley.com/doi/10.1002/hep.26164/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/hep.26164/full )

Exposure to Common Germs Linked to Worse Cognition

MONDAY, March 25 (HealthDay News) -- Infectious burden, a composite serologic measure of exposure to common pathogens, is associated with worse cognition, according to a study published in the March 26 issue of Neurology.

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Exhaled Breath Can ID Acute Decompensated Heart Failure

MONDAY, March 25 (HealthDay News) -- An exhaled breath metabolome is feasible for identifying acute decompensated heart failure, according to a research letter published in the April 2 issue of the Journal of the American College of Cardiology.

Full Text (http://content.onlinejacc.org/article.aspx?articleid=1671100 )

Even the Poorest Handheld Umbrellas Can Block UV Rays

MONDAY, March 25 (HealthDay News) -- Handheld umbrellas are effective at blocking ultraviolet radiation (UVR), according to a study published online March 20 in JAMA Dermatology.

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FDA Approves Inhaler for Cystic Fibrosis Patients

MONDAY, March 25 (HealthDay News) -- The TOBI Podhaler (tobramycin inhalation powder) has been approved by the U.S. Food and Drug Administration to treat cystic fibrosis patients infected with Pseudomonas aeruginosa, a bacterium that can damage the lungs.

More Information (http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm345123.htm )

Attentive Eating Influences Food Intake

MONDAY, March 25 (HealthDay News) -- Being more aware while eating may lower food consumption, according to a study published in the April issue of the American Journal of Clinical Nutrition.

Abstract (http://ajcn.nutrition.org/content/97/4/728.abstract?sid=eed6a1b9-c092-4520-b212-18296e8af958 )Full Text (subscription or payment may be required) (http://ajcn.nutrition.org/content/97/4/728.full )

Peds to Adult Diabetes Care Switch Mars Glycemic Control

MONDAY, March 25 (HealthDay News) -- For youth with type 1 diabetes, the transition from pediatric to adult diabetes care is associated with increased risk of poor glycemic control, according to a study published online March 25 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-1450.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-1450.full.pdf+html )

White Matter Diffusivity Linked to Gulf War Illness Symptoms

MONDAY, March 25 (HealthDay News) -- Fatigue, pain, and hyperalgesia are associated with increased axial diffusivity in the right inferior fronto-occipital fasciculus in veterans with Gulf War Illness, according to a study published online March 20 in PLOS ONE.

Full Text (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058493 )

Nurses Can Resolve Low Complexity, Primary Care Cases

MONDAY, March 25 (HealthDay News) -- Nurses can comparably solve acute, low complexity health problems with similar results to general practitioners, according to a study published online March 21 in the Journal of Advanced Nursing.

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Maternal Grief Linked to Baby's Congenital Heart Disease Risk

MONDAY, March 25 (HealthDay News) -- Children born to mothers who lost a close relative around the time of conception have a slightly higher risk of congenital heart disease, according to a study published online March 25 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-3024.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-3024.full.pdf+html )

Many Mothers Introducing Solid Foods to Infants Too Early

MONDAY, March 25 (HealthDay News) -- About 40 percent of mothers introduce solid food to their infants before the recommended four months of age, with an even higher prevalence for formula-fed infants, according to a study published online March 25 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-2265.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/18/peds.2012-2265.full.pdf+html )

High Mortality, Morbidity With Early-Onset Scoliosis Surgery

MONDAY, March 25 (HealthDay News) -- Surgery for patients with early-onset scoliosis is associated with an 18 percent mortality rate and an 84 percent complication rate, according to research published in the Feb. 15 issue of Spine.

Abstract (http://journals.lww.com/spinejournal/Abstract/2013/02150/Mortality_and_Morbidity_in_Early_Onset_Scoliosis.7.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/spinejournal/Abstract/2013/02150/Mortality_and_Morbidity_in_Early_Onset_Scoliosis.7.aspx )

Antiplatelet Drugs Don't Up ICH Risk in New Study

MONDAY, March 25 (HealthDay News) -- Pre-existing antiplatelet use does not seem to be associated with an increased risk of ischemic hemorrhage (ICH), according to an observational study published in the February issue of Academic Emergency Medicine.

Abstract (http://onlinelibrary.wiley.com/doi/10.1111/acem.12077/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/acem.12077/full )Commentary (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/acem.12067/abstract )

Reading, Writing, Ranting Online Could Be a Web of Rage

MONDAY, March 25 (HealthDay News) -- Reading and writing on rant websites seems to be an unhealthy practice, according to a study published Feb. 20 in Cyberpsychology, Behavior, and Social Networking.

Full Text (http://online.liebertpub.com/doi/full/10.1089/cyber.2012.0130 )

Survey Finds Illegal Firearm Purchases, Thefts Are Common

FRIDAY, March 22 (HealthDay News) -- Licensed firearms retailers report attempts to illegally purchase or steal firearms are common, according to research published online March 11 in Injury Prevention.

Abstract (http://injuryprevention.bmj.com/content/early/2013/03/10/injuryprev-2012-040715.abstract )Full Text (subscription or payment may be required) (http://injuryprevention.bmj.com/content/early/2013/03/10/injuryprev-2012-040715.full )

Higher Mortality Rate Seen in Middle-Aged Diabetes Patients

FRIDAY, March 22 (HealthDay News) -- Middle-aged people with type 2 diabetes, particularly women and those under the age of 55, have a two to three times higher risk of all-cause and cardiovascular mortality than people without diabetes, according to research published online Feb. 22 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1513.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1513.full.pdf+html )

Sports Concussion Management Recommendations Updated

FRIDAY, March 22 (HealthDay News) -- Recommendations for sports concussion and its management have been updated, according to a consensus statement published in the April issue of the British Journal of Sports Medicine.

Abstract (http://bjsm.bmj.com/content/47/5/250.extract )Full Text (http://bjsm.bmj.com/content/47/5/250.full )

Field Stories Can Shape Public Policy for Obesity Prevention

FRIDAY, March 22 (HealthDay News) -- Stories from the field can help highlight policy, systems, and environmental approaches effective in obesity prevention, according to a study published online Feb. 14 in Preventing Chronic Disease.

Full Text (http://www.cdc.gov/pcd/issues/2013/12_0141.htm )

Better Long-Term Outcomes With Low Hep C Viral Load

FRIDAY, March 22 (HealthDay News) -- In patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), low HCV viral load predicts better long-term surgical outcomes, regardless of the serologic eradication of HCV, according to research published in the Feb. 20 issue of the Journal of Clinical Oncology.

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Mobility Impaired May Have Difficulty Accessing Docs

FRIDAY, March 22 (HealthDay News) -- Many U.S. subspecialty practices cannot accommodate patients with mobility impairment, according to a study published in the March 19 issue of the Annals of Internal Medicine.

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No Overall Survival Benefit Tied to Bilateral Oophorectomy

FRIDAY, March 22 (HealthDay News) -- At no age is there an overall survival benefit associated with bilateral oophorectomy compared with ovarian conservation at the time of hysterectomy for benign disease, according to a study published online March 6 in Obstetrics & Gynecology.

Abstract (http://journals.lww.com/greenjournal/Abstract/publishahead/Long_Term_Mortality_Associated_With_Oophorectomy.99867.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/publishahead/Long_Term_Mortality_Associated_With_Oophorectomy.99867.aspx )

Engineered Immune Cells Lead to Leukemia Remission

FRIDAY, March 22 (HealthDay News) -- Five patients with relapsed B cell acute lymphoblastic leukemia (B-ALL) quickly achieved complete remission after treatment with autologous engineered T cells, according to research published in the March 20 issue of Science Translational Medicine.

Abstract (http://stm.sciencemag.org/content/5/177/177ra38.abstract )Full Text (subscription or payment may be required) (http://stm.sciencemag.org/content/5/177/177ra38.full )

Clarithromycin May Be Linked to Cardiovascular Events

FRIDAY, March 22 (HealthDay News) -- For patients with acute exacerbations of chronic obstructive pulmonary disease or community-acquired pneumonia, use of clarithromycin correlates with increased risk of cardiovascular events, according to a study published online March 22 in BMJ.

Full Text (http://www.bmj.com/content/346/bmj.f1235 )

Telehealth in Addition to Usual Care Not Cost-Effective

FRIDAY, March 22 (HealthDay News) -- For adults with chronic health conditions, a telehealth intervention in addition to standard support and treatment is associated with increased costs, with no significant benefit in terms of quality adjusted life years (QALYs), according to a study published online March 22 in BMJ.

Full Text (http://www.bmj.com/content/346/bmj.f1035 )

Impact of Budget Sequestration on Health Care Discussed

THURSDAY, March 21 (HealthDay News) -- The impact of sequestration will have far-reaching consequences in health care, according to a perspective piece published online March 20 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1303266?query=featured_home )

FDA Approves Dotarem for Nervous System MRIs

THURSDAY, March 21 (HealthDay News) -- Dotarem (gadoterate meglumine) has been approved by the U.S. Food and Drug Administration as a contrast agent for use in MRIs of the brain, spine, and other parts of the central nervous system.

More Information (http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm344758.htm )

Most People With Prediabetes in the Dark About Their Condition

THURSDAY, March 21 (HealthDay News) -- Most of the people in the United States with prediabetes, a state that puts them at high risk of developing type 2 diabetes if they do not take measures to prevent that progression, are unaware of their condition, according to research published in the March 22 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

Full Text (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6211a4.htm?s_cid=mm6211a4_w )

Hypertension, APOE Genotype Add to Amyloid Deposits

THURSDAY, March 21 (HealthDay News) -- Hypertension in combination with the apolipoprotein E (APOE) genotype increases amyloid deposits in cognitively healthy middle-aged and older adults, according to a study published online March 18 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1669203#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1669203 )

Race Influences Lower Extremity Ischemia Treatment

THURSDAY, March 21 (HealthDay News) -- Even after adjustment for confounding variables, black patients are significantly more likely to undergo amputation for critical lower extremity ischemia, according to a study published online March 20 in JAMA Surgery.

Abstract (http://archsurg.jamanetwork.com/article.aspx?articleid=1669979#Abstract )Full Text (subscription or payment may be required) (http://archsurg.jamanetwork.com/article.aspx?articleid=1669979 )Editorial (subscription or payment may be required) (http://archsurg.jamanetwork.com/article.aspx?articleid=1669980 )

Suicide Ideation, Attempts Higher in Children With Autism

THURSDAY, March 21 (HealthDay News) -- Children with autism have much higher rates of suicide ideation and suicide attempts than typical children, according to a study published in the January issue of Research in Autism Spectrum Disorders.

Abstract (http://www.sciencedirect.com/science/article/pii/S1750946712000931 )Full Text (subscription or payment may be required) (http://www.sciencedirect.com/science/article/pii/S1750946712000931 )

Hypospadias Not Related to Organic Diet During Pregnancy

THURSDAY, March 21 (HealthDay News) -- Although no obvious relationship between organic diet during pregnancy and hypospadias has been found, frequent consumption of non-organic high-fat dairy products during pregnancy might be associated with increased odds of hypospadias, according to research published in the March issue of Urology.

Abstract (http://www.jurology.com/article/S0022-5347(12)05098-7/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)05098-7/fulltext )Editorial (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)05843-0/fulltext )

Endocrine Society Urges Better Standards for Estradiol Testing

THURSDAY, March 21 (HealthDay News) -- A new position statement published by The Endocrine Society recommends that estradiol measurement assays and reference ranges be standardized and that the health care community work toward improving the accessibility of accurate estradiol testing methods; the position statement was published online March 5 in the Journal of Clinical Endocrinology & Metabolism.

Abstract (http://jcem.endojournals.org/content/early/2013/03/05/jc.2012-3780.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/03/05/jc.2012-3780.full.pdf+html )

Heart-Healthy Lifestyle Can Also Reduce Cancer Risk

THURSDAY, March 21 (HealthDay News) -- Subjects who are enrolled in the Atherosclerosis Risk in Communities (ARIC) study and are meeting goals for six to seven ideal health metrics have a 51 percent lower risk of incident cancer than those not meeting any goals for ideal health metrics, according to research published online March 18 in Circulation.

Abstract (http://circ.ahajournals.org/content/early/2013/03/13/CIRCULATIONAHA.112.001183.abstract )Full Text (http://circ.ahajournals.org/content/early/2013/03/13/CIRCULATIONAHA.112.001183.full.pdf+html )

Annual BP Checks May Improve Hypertension Identification

THURSDAY, March 21 (HealthDay News) -- For previously normotensive adults, an annual office-based hypertension screening strategy is associated with improved specificity while maintaining sensitivity, according to a study published in the March/April issue of Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/116.abstract )Full Text (http://www.annfammed.org/content/11/2/116.full )

Pediatric Malaria Vaccine Efficacy Declines With Time

WEDNESDAY, March 20 (HealthDay News) -- A pediatric malaria vaccine reduces episodes of clinical malaria but its efficacy declines over time, according to a study in the March 21 issue of The New England Journal of Medicine.

Abstract (http://www.nejm.org/doi/full/10.1056/NEJMoa1207564 )Full Text (http://www.nejm.org/doi/full/10.1056/NEJMoa1207564#t=article )

Effect of Immigration Status on Medicaid Eligibility Discussed

WEDNESDAY, March 20 (HealthDay News) -- Under the Affordable Care Act, a considerable proportion of low-income uninsured adults will be ineligible for Medicaid coverage due to their immigration status, and their main providers are likely to be safety-net health care providers, according to a March report published by the State Health Access Data Assistance Center.

More Information (http://www.rwjf.org/en/research-publications/find-rwjf-research/2013/03/state-estimates-of-the-low-income-uninsured-not-eligible-for-the.html )

Childrens' Norovirus-Related Gastroenteritis Still a Burden

WEDNESDAY, March 20 (HealthDay News) -- Norovirus-associated illness is the leading cause of medically attended acute gastroenteritis in young children, according to a study published in the March 21 issue of the New England Journal of Medicine.

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Closure of Patent Foramen Ovale Doesn't Beat Medical Tx

WEDNESDAY, March 20 (HealthDay News) -- For patients with patent foramen ovale, percutaneous closure is not superior to medical therapy for the risk of recurrent embolic events or death, or for reducing recurrent ischemic stroke, according to two studies published in the March 21 issue of the New England Journal of Medicine.

Abstract - Meier (http://www.nejm.org/ )Full Text (subscription or payment may be required)Abstract - CarrollFull Text (subscription or payment may be required)

Intensive Glycemic Control Linked to Highest Weight Gains

WEDNESDAY, March 20 (HealthDay News) -- Weight gain is higher in patients with type 2 diabetes mellitus (T2DM) who receive more intensive glycemic control treatment and is associated with a reduction of A1C from baseline, according to research published online Feb. 14 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/12/dc12-1391.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/12/dc12-1391.full.pdf+html )

High-Potency Statins Up Acute Kidney Injury Hospitalizations

WEDNESDAY, March 20 (HealthDay News) -- For patients with non-chronic kidney disease, high-potency statin treatment is associated with an increased risk of hospitalization for acute kidney injury, according to a study published online March 19 in the BMJ.

Full Text (http://www.bmj.com/content/346/bmj.f880 )Editorial (subscription or payment may be required) (http://www.bmj.com/content/346/bmj.f1531 )

Prevalence of Parent-Reported Autism Up in School Children

WEDNESDAY, March 20 (HealthDay News) -- The prevalence of parent-reported autism spectrum disorder (ASD) in school-aged children appears to have increased, but that may be due to new diagnoses in children whose ASD had previously gone unrecognized, according to research published in the U.S. Centers for Disease Control and Prevention's March 20 National Health Statistics Reports.

More Information (http://www.cdc.gov/nchs/data/nhsr/nhsr065.pdf )

HIV Prevalence Is High Among High-Risk Heterosexuals

WEDNESDAY, March 20 (HealthDay News) -- The prevalence of HIV infection is high among low socioeconomic heterosexuals living in areas with high rates of AIDS in 2010, according to research published in the March 15 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

Full Text (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6210a2.htm?s_cid=mm6210a2_w )

Ethics of Peds Countermeasure Research Discussed

WEDNESDAY, March 20 (HealthDay News) -- Pediatric research on medical countermeasures should present no more than minimal risk to participants, and should follow a specific framework if there is a minor increase over minimal risk, according to a perspective piece published online March 19 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1302093?query=featured_home )

Chlorthalidone No Better Than Hydrochlorothiazide for HTN

WEDNESDAY, March 20 (HealthDay News) -- For older adults with hypertension, chlorthalidone is not associated with fewer adverse cardiovascular events or death, but correlates with increased hypokalemia compared with hydrochlorothiazide, according to a study published in the March 19 issue of the Annals of Internal Medicine.

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Molluscum Contagiosum Virus Linked to Pubic Hair Removal

WEDNESDAY, March 20 (HealthDay News) -- The incidence of sexually transmitted molluscum contagiosum virus (STMC) may be linked to hair removal in the genital area, according to a letter published online March 18 in Sexually Transmitted Infections.

Abstract (http://sti.bmj.com/content/early/2013/02/15/sextrans-2012-050982.extract )Full Text (subscription or payment may be required) (http://sti.bmj.com/content/early/2013/02/15/sextrans-2012-050982.full )

Manual Osteopathic Treatment Improves Chronic Back Pain

WEDNESDAY, March 20 (HealthDay News) -- Treatment of nonspecific chronic low back pain with osteopathic manual treatment (OMT) is associated with moderate or substantial improvements in low back pain, according to a study published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/122.abstract )Full Text (http://www.annfammed.org/content/11/2/122.full )

Docs Decide on Duration of Antibiotics in Long-Term Care

WEDNESDAY, March 20 (HealthDay News) -- Prescriber preference rather than patient characteristics influences the duration of antibiotic courses in long-term care residents, according to research published online March 18 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1669102#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1669102 )Editorial (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1669109 )

Total Knee Replacement Poses Large Public Health Burden

WEDNESDAY, March 20 (HealthDay News) --The prevalence of total knee replacement is estimated at 4.2 percent for U.S. adults aged 50 years and older, according to a study published in the March 6 issue of The Journal of Bone & Joint Surgery.

Abstract (http://jbjs.org/article.aspx?articleid=1555390 )Full Text (subscription or payment may be required) (http://jbjs.org/article.aspx?articleid=1555390 )

ER Discharge Dx/Disposition Discordant With Chief Complaint

TUESDAY, March 19 (HealthDay News) -- A considerable proportion of patients with emergency department visits with the same presenting complaint as those ultimately given a primary care-treatable diagnosis require immediate emergency care or hospital admission, according to a study published in the March 20 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1669818#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1669818 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669802 )

Long-Term Mortality Up for Under-50s With First Stroke

TUESDAY, March 19 (HealthDay News) -- For adults aged 18 to 50 years with acute stroke, 20-year mortality is higher than expected, according to a study published in the March 20 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1669817#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669817 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669801 )

One in Three U.S. Seniors Dies With Alzheimer's or Dementia

TUESDAY, March 19 (HealthDay News) -- Alzheimer's deaths are increasing, with one in three seniors currently expected to die with Alzheimer's or another form of dementia, according to a report published by the Alzheimer's Association.

More Information (http://www.alz.org/national/documents/facts_and_figures_2013_press_release.pdf )

Sepsis Drug Eritoran Not Superior to Placebo

TUESDAY, March 19 (HealthDay News) -- Eritoran, a synthetic analog of lipid A and a toll-like receptor 4 antagonist, is no better than placebo in reducing mortality in patients with severe sepsis, according to a study published in the March 20 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1669798#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669798 )

Variation Seen in Vena Cava Filter Use Among Hospitals

TUESDAY, March 19 (HealthDay News) -- The frequency of vena cava filter (VCF) use in patients with acute venous thromboembolism (VTE) varies widely and depends primarily on hospital practice, even after adjustment for clinical and socioeconomic factors, according to research published online March 18 in JAMA Internal Medicine.

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Skim Milk Does Not Prevent Obesity in Young Children

TUESDAY, March 19 (HealthDay News) -- For preschool children, consumption of 1 percent/skim milk is associated with overweight/obesity, according to a study published online March 18 in the Archives of Disease in Childhood.

Abstract (http://adc.bmj.com/content/early/2013/02/13/archdischild-2012-302941.abstract )Full Text (subscription or payment may be required) (http://adc.bmj.com/content/early/2013/02/13/archdischild-2012-302941.full )

Maternal Vitamin D Not Linked to Child Bone Mineral Content

TUESDAY, March 19 (HealthDay News) -- There is no association between maternal 25-hydroxyvitamin D (25[OH]D) concentration and bone mineral content (BMC) in offspring at age 9 to 10 years, according to a study published online March 19 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62203-X/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62203-X/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60098-7/fulltext )

Aristolochic Acid Nephropathy, a Global Health Problem

TUESDAY, March 19 (HealthDay News) -- Although the first description of a rapidly progressive nephropathy associated with the consumption of aristolochic acid (AA) found in Chinese herbs was first reported 20 years ago, AA-induced nephropathy remains a worldwide health concern due to the lack of regulation on herbal medication and the easy availability of such medications online, according to a review published in the March 19 issue of the Annals of Internal Medicine.

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Conflict-of-Interest Disclosures Common at 2011 AAOS Meeting

TUESDAY, March 19 (HealthDay News) -- At the 2011 American Academy of Orthopaedic Surgeons (AAOS) annual meeting, voluntarily disclosed conflicts of interest were common, especially for featured symposia, according to a study published in the March 6 issue of The Journal of Bone & Joint Surgery.

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Barrier Assessment Improves Care for Elderly With Diabetes

TUESDAY, March 19 (HealthDay News) -- For older adults with diabetes, an active intervention involving assessment of barriers to self-care and development of strategies to cope with these barriers is superior to usual care, according to research published in the March issue of Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/36/3/543.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/36/3/543.full )

AAN Updates Guidelines for Sports Concussion Management

MONDAY, March 18 (HealthDay News) -- The risks, diagnosis, and management of sports concussion have been reviewed in updated guidelines published online March 18 by the American Academy of Neurology (AAN) in Neurology.

Abstract (http://www.neurology.org/content/early/2013/03/15/WNL.0b013e31828d57dd.abstract )Full Text (http://www.neurology.org/content/early/2013/03/15/WNL.0b013e31828d57dd.full.pdf+html )Editorial (http://www.neurology.org/content/early/2013/03/15/WNL.0b013e31828d9c13.full.pdf+html )

USPSTF: Insufficient Evidence for ABI Screening for PAD, CVD

MONDAY, March 18 (HealthDay News) -- The U.S. Preventive Services Task Force has found that there is currently insufficient evidence to determine whether the ankle brachial index (ABI) is beneficial for screening for peripheral artery disease (PAD) and predicting the risk of cardiovascular disease.

Draft Recommendation Statement (http://www.uspreventiveservicestaskforce.org/draftrec3.htm )Comment on Recommendations (http://www.uspreventiveservicestaskforce.org/tfcomment.htm )

Older Women Can Safely Undergo Mammography Biennially

MONDAY, March 18 (HealthDay News) -- Women 50 to 74 years old can safely undergo mammography every two years instead of annually, while women 40 to 49 years old should only undergo annual mammography if they have extremely dense breasts, according to a study published online March 18 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1669103#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1669103 )

Exercise Improves Quality of Life in Type 2 Diabetes

MONDAY, March 18 (HealthDay News) -- For people with type 2 diabetes mellitus (T2DM), a nine-month aerobic and resistance training program significantly improves quality of life (QOL) compared with no exercise, according to research published online Feb. 12 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1153.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1153.long )

Cellphone Use While Driving Varies From 21 to 69 Percent

MONDAY, March 18 (HealthDay News) -- The prevalence of talking on a cellphone while driving ranges from 21 to 69 percent across the United States and seven European countries, according to research published in the March 15 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

Full Text (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6210a1.htm?s_cid=mm6210a1_e )

Data Insufficient to Link Declines in Breast Cancer, HRT Use

MONDAY, March 18 (HealthDay News) -- Evidence does not definitively link the decline in the use of hormone replacement therapy (HRT) to a fall in the incidence of breast cancer, according to the last in a series of critiques published in the April issue of the Journal of Family Planning & Reproductive Health Care.

Abstract (http://jfprhc.bmj.com/content/39/2/80.abstract )Full Text (subscription or payment may be required) (http://jfprhc.bmj.com/content/39/2/80.full )Commentary (http://jfprhc.bmj.com/content/39/2/72.full )

Reasons for Refusal of HPV Differ From Other Vaccines

MONDAY, March 18 (HealthDay News) -- Parents who do not have their teenagers immunized against human papillomavirus (HPV) most often say that they have safety concerns or that their child is not sexually active, which differs from their refusal of other vaccines, according to a study published online March 18 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/12/peds.2012-2384.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/12/peds.2012-2384.full.pdf+html )

Black Children Less Likely to Be Prescribed Antibiotics

MONDAY, March 18 (HealthDay News) -- Black children are less likely to be prescribed antibiotics and to be diagnosed with conditions that require antibiotics, even when treated by the same doctor, according to research published online March 18 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/12/peds.2012-2500.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/12/peds.2012-2500.full.pdf+html )

Evidence Indicates Link for Shift Work, Ovarian Cancer

MONDAY, March 18 (HealthDay News) -- Shift work may be associated with an increased risk of ovarian cancer, according to a study published in the April issue of Occupational & Environmental Medicine.

Abstract (http://oem.bmj.com/content/70/4/231.short?g=w_oem_current_tab )Full Text (subscription or payment may be required) (http://oem.bmj.com/content/70/4/231.full )Editorial (subscription or payment may be required) (http://oem.bmj.com/content/70/4/283.extract )

Telemedicine Is Useful for Parkinson's Disease Patients

MONDAY, March 18 (HealthDay News) -- Providing specialty care for patients with Parkinson's disease (PD) using Web-based video conferencing is feasible, provides value to patients, and offers clinical benefits similar to those of in-person visits, while saving patients time and travel, according to research published online March 11 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1663362#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1663362 )

Pharmacist-Led Home BP Program Shows Success

MONDAY, March 18 (HealthDay News) -- Compared with usual care, a pharmacist-led home blood pressure monitoring (HBPM) intervention called Heart360 results in greater blood pressure (BP) reductions, superior BP control, and higher patient satisfaction, according to research published online March 5 in Circulation: Cardiovascular Quality and Outcomes.

Abstract (http://circoutcomes.ahajournals.org/content/early/2013/03/05/CIRCOUTCOMES.112.968172.abstract )Full Text (subscription or payment may be required) (http://circoutcomes.ahajournals.org/content/early/2013/03/05/CIRCOUTCOMES.112.968172.full.pdf+html )

Key Variables Examined in Gestational Diabetes Advance

MONDAY, March 18 (HealthDay News) -- For women with gestational diabetes mellitus (GDM), clinical and genetic factors including higher pre-pregnancy body mass index are associated with development of type 2 diabetes mellitus (T2DM), according to a study published online March 7 in the Journal of Clinical Endocrinology.

Abstract (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-3324.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/03/07/jc.2012-3324.long )

BP Shifts Tied to Mortality Risk for Blacks With Kidney Disease

FRIDAY, March 15 (HealthDay News) -- Higher systolic blood pressure visit-to-visit variability (SBV) is independently associated with overall and cardiovascular mortality in African-Americans with chronic kidney disease (CKD), according to a study published online March 14 in the Clinical Journal of the American Society of Nephrology.

Abstract (http://cjasn.asnjournals.org/content/early/2013/03/12/CJN.10131012.abstract )Full Text (subscription or payment may be required) (http://cjasn.asnjournals.org/content/early/2013/03/12/CJN.10131012.full )

Final Rule in Notice of Benefit, Payment Parameters Issued

FRIDAY, March 15 (HealthDay News) -- The final rule of the Department of Health and Human Services (HHS) Notice of Benefit and Payment Parameters for 2014, which expands on existing standards, has been released.

More Information (http://content.govdelivery.com/bulletins/gd/USCMS-6ebb0f )

Robotic Surgery Not Best for Hysterectomy, ACOG Says

FRIDAY, March 15 (HealthDay News) -- Robotic surgery is not the only, the best, or the most cost-efficient method for a minimally invasive hysterectomy, according to a statement published March 14 by the American College of Obstetricians & Gynecologists (ACOG).

More Information (http://www.acog.org/About_ACOG/News_Room/News_Releases/2013/Statement_on_Robotic_Surgery )

Oral Melatonin Has No Effect on Appetite in Advanced Cancer

FRIDAY, March 15 (HealthDay News) -- Oral melatonin does not improve appetite, weight, or quality of life for patients with cachexia due to advanced cancer, according to research published online Feb. 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.43.6766.short?rss=1 )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.43.6766.full.pdf+html )Editorial (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.48.3149.full.pdf+html )

Exercise, Counseling Cut Days Off From Back Pain in Recruits

FRIDAY, March 15 (HealthDay News) -- Neuromuscular exercise and counseling decrease the number of days off due to low back pain (LBP) among young men serving in the military, according to a study published in the March 1 issue of Spine.

Abstract (http://journals.lww.com/spinejournal/Abstract/2013/03010/Neuromuscular_Exercise_and_Counseling_Decrease.2.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/spinejournal/Abstract/2013/03010/Neuromuscular_Exercise_and_Counseling_Decrease.2.aspx )

About 14 Percent of Moms Face Postpartum Depression

FRIDAY, March 15 (HealthDay News) -- About 14 percent of mothers are depressed postpartum, with a postpartum onset in most cases, and with the most common diagnosis being major depressive disorder with comorbid anxiety disorders, according to a study published online March 13 in JAMA Psychiatry.

Abstract (http://archpsyc.jamanetwork.com/article.aspx?articleid=1666651#Abstract )Full Text (subscription or payment may be required) (http://archpsyc.jamanetwork.com/article.aspx?articleid=1666651 )

High-Fat Dairy Linked to All-Cause, Breast Cancer Mortality

FRIDAY, March 15 (HealthDay News) -- For women with a breast cancer diagnosis, high-fat dairy consumption is associated with a higher mortality risk, according to a study published online March 14 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt027.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt027.full )Editorial (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt052.extract )

Health Insurance Exchanges Will Mainly Be Run by Feds

FRIDAY, March 15 (HealthDay News) -- More than half of the states within the United States will allow the federal government to establish health insurance exchanges, according to a report issued by the Henry J. Kaiser Family Foundation.

More Information (http://www.statehealthfacts.org/comparemaptable.jsp?ind=962&cat=17 )

Cardio Risks Need Evaluation Before Prescribing Statins

FRIDAY, March 15 (HealthDay News) -- Physicians may not adequately consider a patient's cardiovascular risk when prescribing statins as preventive therapy, according to a research letter published online March 11 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1666428 )

Cardiac Benefits of Physical Activity in Diabetes Studied

FRIDAY, March 15 (HealthDay News) -- Adults with clinical diabetes are more likely to experience cardiovascular death than those without diabetes; however, physical activity may negate the negative impact of diabetes on cardiovascular mortality, according to a study published in the March issue of Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/36/3/690.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/36/3/690.full )

Pharmaceutical Companies Are Reducing Promotional Spending

FRIDAY, March 15 (HealthDay News) -- Pharmaceutical companies have been reducing the amount of money they spend on promotion to consumers and providers over the past decade and spend much less to promote biologics compared with small molecule drugs, according to a study published online March 4 in PLOS ONE.

Full Text (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055504 )

Family-Centered Advanced Care Planning Benefits Ailing Teens

THURSDAY, March 14 (HealthDay News) -- Family-centered advanced care planning (ACP) enables families to better understand and agree on end-of-life decisions for adolescents with cancer, according to a study published online March 11 in JAMA Pediatrics.

Abstract (http://archpedi.jamanetwork.com/article.aspx?articleid=1663080#Abstract )Full Text (subscription or payment may be required) (http://archpedi.jamanetwork.com/article.aspx?articleid=1663080 )

Rules Must Evolve to Allow New Drugs for Early Alzheimer's

THURSDAY, March 14 (HealthDay News) -- Given the shift in the focus of drug development for Alzheimer's disease toward earlier disease stages, before the onset of dementia, regulatory guidelines need to evolve, according to a perspective piece published online March 13 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1302513?query=featured_home )

Stimulated Reporting Accounts for High Dabigatran Bleeding

THURSDAY, March 14 (HealthDay News) -- The increased number of post-marketing reports of bleeding associated with use of dabigatran seems to be an example of stimulated reporting and may not represent an increased bleeding risk, according to a perspective piece published online March 13 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1302834?query=featured_home )

Childhood Obesity Tied to Worse Hospital Outcomes

THURSDAY, March 14 (HealthDay News) -- Childhood obesity may be a risk factor for worse outcomes in hospitalized children with critical illness, oncologic diagnoses, or transplants, according to a review published online March 11 in JAMA Pediatrics.

Abstract (http://archpedi.jamanetwork.com/article.aspx?articleid=1663076#Abstract )Full Text (subscription or payment may be required) (http://archpedi.jamanetwork.com/article.aspx?articleid=1663076 )

Vitamin D3 Supplementation Lowers Systolic BP in Blacks

THURSDAY, March 14 (HealthDay News) -- Vitamin D3 (cholecalciferol) supplementation lowers systolic blood pressure in blacks, according to a study published in the April issue of Hypertension.

Abstract (http://hyper.ahajournals.org/content/61/4/779.abstract )Full Text (subscription or payment may be required) (http://hyper.ahajournals.org/content/61/4/779.full )

Prescribing ADHD Drugs to Healthy Children Not Justified

THURSDAY, March 14 (HealthDay News) -- Prescribing neuroenhancing drugs, such as those used to treat attention-deficit/hyperactivity disorder, to healthy children and teens to improve memory or cognitive function is unjustified and inadvisable, according to position paper published online March 13 in Neurology.

Abstract (http://www.neurology.org/content/early/2013/03/13/WNL.0b013e318289703b.abstract )Full Text (http://www.neurology.org/content/early/2013/03/13/WNL.0b013e318289703b.full.pdf+html )

Geriatric Factors Can Foretell Tolerances to Chemotherapy

THURSDAY, March 14 (HealthDay News) -- For elderly patients with metastatic colorectal cancer (mCRC), scores on the Mini-Mental State Examination (MMSE) and Instrumental Activities of Daily Living (IADL) were predictive of severe toxicity or unexpected hospitalization after fluorouracil-based chemotherapy with or without irinotecan (IRI), according to research published online March 4 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.9894.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.9894.full.pdf+html )

Self-Reported Vision Loss Is Associated With Depression

THURSDAY, March 14 (HealthDay News) -- Self-reported vision loss is significantly associated with depression, according to a study published online March 7 in JAMA Ophthalmology.

Abstract (http://archopht.jamanetwork.com/article.aspx?articleid=1660943#Abstract )Full Text (http://archopht.jamanetwork.com/article.aspx?articleid=1660943 )

ERs Need to Do More to Inform Parents on Child Seat Safety

THURSDAY, March 14 (HealthDay News) -- Although the availability of child passenger safety resources varies by practice setting, only one-third to one-half of emergency department physicians recommend replacement of a child's car seat after a motor vehicle collision (MVC), according to research published in the March issue of Pediatric Emergency Care.

Abstract (http://journals.lww.com/pec-online/pages/articleviewer.aspx?year=2013&issue=03000&article=00010&type=abstract )Full Text (subscription or payment may be required) (http://journals.lww.com/pec-online/pages/articleviewer.aspx?year=2013&issue=03000&article=00010&type=abstract )

Medicare Cancer Spending Has Little Effect on Survival

THURSDAY, March 14 (HealthDay News) -- Medicare spending for advanced cancer care has substantial regional variation, according to a study published online March 12 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt025.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt025.full )

Medicare Patients Enrolled in Hospice Receive Better Care

THURSDAY, March 14 (HealthDay News) -- Medicare patients who enroll in hospice care receive better care at a lower cost, with the greatest savings if they enroll 15 to 30 days before death, according to a study published in the March issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/3/552.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/3/552.full )

Family Presence During CPR Has Positive Effect for Family

WEDNESDAY, March 13 (HealthDay News) -- Family presence during cardiopulmonary resuscitation (CPR) at home correlates with positive psychological variables for the family; and survival and readmission among older patients who survive an in-hospital cardiac arrest is related to demographic variables and neurologic status at discharge, according to two studies published in the March 14 issue of the New England Journal of Medicine.

Full Text - Jabre (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1203366 )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1300397 )Full Text - Chan (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1200657 )

MRI Assessment Doesn't ID Recurrent Sciatica at One Year

WEDNESDAY, March 13 (HealthDay News) -- For patients treated for sciatica and lumbar-disc herniation, magnetic resonance imaging (MRI) performed at one year does not distinguish between those with and without favorable outcome, according to a study published in the March 14 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1209250 )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1215599 )

FDA Reaffirms Azithromycin Tie to Heart Rhythm Abnormalities

WEDNESDAY, March 13 (HealthDay News) -- The drug labels on azithromycin (Zithromax, Zmax) have been updated to strengthen the Warnings and Precautions section with information relating to abnormal changes in the electrical activity of the heart, which may lead to a potentially fatal irregular heart rhythm, according to a March 12 safety announcement issued by the U.S. Food and Drug Administration.

More Information (http://www.fda.gov/Drugs/DrugSafety/ucm341822.htm )

Small Benefit of Adjunctive Antipsychotics for Depression

WEDNESDAY, March 13 (HealthDay News) -- Atypical antipsychotic drugs for the adjunctive treatment of depression are associated with relatively small benefits, no improvement in function or quality of life, and adverse events, according to research published online March 12 in PLOS Medicine.

Full Text (http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001403;jsessionid=6EFCCAB52BB42E698E5315E80D22667C )

2009 H1N1 Vaccine Tied to Small Risk of Guillain-Barré Syndrome

WEDNESDAY, March 13 (HealthDay News) -- The monovalent inactivated influenza (H1N1) 2009 vaccine is associated with a small but significant increase in the risk of Guillain-Barré syndrome in the United States, according to a meta-analysis published online March 13 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62189-8/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62189-8/fulltext )

Post-PCI Bleeding Linked to Increased In-Hospital Mortality

WEDNESDAY, March 13 (HealthDay News) -- Post-percutaneous coronary intervention (PCI) bleeding events are associated with an increased risk of in-hospital mortality, according to a study published in the March 13 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1667092#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1667092 )

Primary Care Noninferior for Management of Sleep Apnea

WEDNESDAY, March 13 (HealthDay News) -- Management of obstructive sleep apnea in a primary care setting is noninferior to care at specialist sleep centers, according to a study published in the March 13 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1667091#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1667091 )

Post-Stroke Walking Improves Survivors' Quality of Life

WEDNESDAY, March 13 (HealthDay News) -- Walking improves the physical health component of quality of life measures in stroke survivors, according to a study published online March 7 in Stroke.

Abstract (http://stroke.ahajournals.org/content/early/2013/03/07/STROKEAHA.111.000642.abstract )Full Text (subscription or payment may be required) (http://stroke.ahajournals.org/content/early/2013/03/07/STROKEAHA.111.000642.full.pdf+html )

AMA Files Brief Contesting Insurer's Payment Practices

WEDNESDAY, March 13 (HealthDay News) -- A landmark case examining the question of whether physicians can bring a class arbitration against a health insurer who has underpaid them is currently before the U.S. Supreme Court, in a brief filed by the Litigation Center of the American Medical Association and State Medical Societies and the Medical Society of New Jersey.

More Information (http://www.ama-assn.org/ama/pub/physician-resources/legal-topics/litigation-center.page? )

Sentinel Injuries Are Common in Infants Who Are Abused

WEDNESDAY, March 13 (HealthDay News) -- Sentinel injuries are common among infants who suffer abuse and are rare in those who are evaluated for abuse and found to not be abused, according to a study published online March 11 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-2780.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-2780.full.pdf+html )

Neck Injuries Tied to Higher Costs for Patients, Spouses

WEDNESDAY, March 13 (HealthDay News) -- Neck injuries are associated with significant health, social, and economic consequences for patients and their spouses, according to research published in the March 1 issue of Spine.

Abstract (http://journals.lww.com/spinejournal/Abstract/2013/03010/Health,_Social,_and_Economic_Consequences_of_Neck.14.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/spinejournal/Abstract/2013/03010/Health,_Social,_and_Economic_Consequences_of_Neck.14.aspx )

Wide Variation in Cesarean Rates Across U.S. Hospitals

WEDNESDAY, March 13 (HealthDay News) -- Rates of cesarean delivery vary about 10-fold across a sample of U.S. hospitals nationwide, according to a study published in the March issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/3/527.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/3/527.full )

Psycho-Oncologic Interventions May Be Beneficial for Adults

TUESDAY, March 12 (HealthDay News) -- For adults with cancer, psycho-oncologic interventions, such as relaxation, individual and group psychotherapy, and psychoeducation, may be effective in producing significant small-to-medium improvement in patients' emotional distress and quality of life, according to a study published in the Feb. 20 issue of the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/31/6/782.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/31/6/782.full.pdf+html )

Patients With Diabetes Don't Wear Custom Footwear Enough

TUESDAY, March 12 (HealthDay News) -- Adherence rates for wearing custom-made footwear are inadequate for patients with diabetes with a recently healed plantar foot ulcer, according to a study published online Jan. 15 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1330.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1330.full.pdf+html )

Smoking Cessation Cuts Cardiac Risk, Despite Weight Gain

TUESDAY, March 12 (HealthDay News) -- Smoking cessation reduces the risk of cardiovascular disease in people without diabetes, even after taking subsequent weight gain into account, according to a study in the March 13 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1667090#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1667090 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1667068 )

Breastfeeding Does Not Reduce Obesity Risk at Age 11.5

TUESDAY, March 12 (HealthDay News) -- While promoting breastfeeding increases breastfeeding rates, it has no effect on the risk of overweight or obesity in children at 11.5 years of age, according to a study in the March 13 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1667089#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1667089 )

More Gun Laws Linked to Fewer Gun Deaths

TUESDAY, March 12 (HealthDay News) -- States with more firearm laws have a lower rate of gun deaths overall and by suicide and homicide, according to a study published online March 6 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1661390#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1661390 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1661391 )

Worldwide, Contraceptive Prevalence Up Since 1990

TUESDAY, March 12 (HealthDay News) -- Since 1990, contraceptive prevalence has increased worldwide and the unmet need for family planning has decreased, but the absolute number of women with a demand for contraception is likely to increase by 2015, according to a study published online March 12 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62204-1/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62204-1/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60588-7/fulltext )

$120 Million to Be Sequestered From Health Centers in 2013

TUESDAY, March 12 (HealthDay News) -- Budget sequestration, which is expected to reduce federal spending, is likely to result in a $120 million loss in grant funding for the nation's 1,200 community health centers in 2013, according to a report published by the Geiger Gibson/ RCHN Community Health Foundation Research Collaborative.

More Information (http://sphhs.gwu.edu/departments/healthpolicy/publications/GGRCHN.pdf )

Salmonella Typhimurium Outbreak Traced to Frogs

MONDAY, March 11 (HealthDay News) -- An outbreak of primarily pediatric Salmonella Typhimurium infections in the United States has been traced to aquatic African dwarf frogs kept as pets, according to a study published online March 11 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-2031.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-2031.full.pdf+html )

More Evidence of Waning Immunity of Pertussis Vaccine

MONDAY, March 11 (HealthDay News) -- Children who receive five doses of the acellular pertussis vaccine (DTaP) have an increasing risk of developing the illness in the six years after the last dose, supporting the concept of waning vaccine immunity and possibly explaining the increasing proportion of cases among 7- to 10-year-old children, according to a study published online March 11 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-1928.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/03/06/peds.2012-1928.full.pdf+html )

Acute Physical Exercise Improves Executive Function

MONDAY, March 11 (HealthDay News) -- Acute physical exercise improves executive function in children, adolescents, and young adults, according to a meta-analysis published online March 6 in the British Journal of Sports Medicine.

Abstract (http://bjsm.bmj.com/content/early/2013/02/13/bjsports-2012-091441.short )Full Text (subscription or payment may be required) (http://bjsm.bmj.com/content/early/2013/02/13/bjsports-2012-091441.full )

Processed Meat Consumption Linked to Higher Mortality Risk

MONDAY, March 11 (HealthDay News) -- Processed meat consumption is linked to an increased risk of mortality, according to a study published in the March issue of BMC Medicine.

Abstract (http://www.biomedcentral.com/1741-7015/11/63/abstract )Full Text (http://www.biomedcentral.com/1741-7015/11/63 )

FDA Encourages Opioid Prescribers to Pursue Training

MONDAY, March 11 (HealthDay News) -- Prescribers of extended-release/long-acting (ER/LA) opioid analgesics are encouraged to participate in continuing medical education (CME) provided by manufacturers of these analgesics, according to an open letter published March 1 by the U.S. Food and Drug Administration.

More Information (http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/ucm330614.htm )

New Pap Guidelines May Delay Adenocarcinoma Diagnosis

FRIDAY, March 8 (HealthDay News) -- Recent revisions in national guidelines for cervical cancer screening may affect clinicians' ability to diagnosis adenocarcinoma in situ (AIS), particularly in young patients, according to a study published online March 6 in Obstetrics & Gynecology.

Abstract (http://journals.lww.com/greenjournal/Abstract/publishahead/Potential_Effects_of_Updated_Pap_Test_Screening.99877.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/publishahead/Potential_Effects_of_Updated_Pap_Test_Screening.99877.aspx )

Shelf Life of Blood Appears Shorter Than Thought

FRIDAY, March 8 (HealthDay News) -- Red blood cells stored longer than three weeks begin to lose their flexibility, according to a small study published online Feb. 28 in Anesthesia & Analgesia.

Abstract (http://www.anesthesia-analgesia.org/content/early/2013/02/27/ANE.0b013e31828843e6.abstract?sid=4c4b6ed8-c103-4f21-983c-959eda016078 )Full Text (subscription or payment may be required) (http://www.anesthesia-analgesia.org/content/early/2013/02/27/ANE.0b013e31828843e6.full.pdf+html )

PTSD Symptoms Common After Breast Cancer Diagnosis

FRIDAY, March 8 (HealthDay News) -- Following a diagnosis of breast cancer, nearly one-quarter of women report symptoms of posttraumatic stress disorder (PTSD), according to a study published online Feb. 21 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/02/21/jnci.djt024.abstract?sid=b506bcc9-51f3-473b-afdd-8dd5e181eac6 )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/02/21/jnci.djt024.full )

Little Evidence Red Flags Are Useful in Detecting Spinal Woes

FRIDAY, March 8 (HealthDay News) -- Researchers have doubts as to the diagnostic accuracy or usefulness of red flag indicators to detect or exclude spinal malignancy in patients with low back pain (LBP), according to research published online Feb. 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008686.pub2/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008686.pub2/full )

Neonatal Size Unaffected by Gestational Diabetes Drugs

FRIDAY, March 8 (HealthDay News) -- Women with gestational diabetes mellitus treated with metformin or insulin have similar changes in markers of metabolic status and no differences in offspring birth weight, according to a study published in the March issue of Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/36/3/529.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/36/3/529.full )

Risk Factors ID'd for Massive Blood Loss in Scoliosis Surgery

FRIDAY, March 8 (HealthDay News) -- For patients undergoing scoliosis surgery, the risk of massive blood loss is increased with preoperative Cobb angles bigger than 50 degrees and for those undergoing osteotomy or fusion of more than six levels, according to a study published in the Feb. 15 issue of Spine.

Abstract (http://journals.lww.com/spinejournal/Abstract/2013/02150/Prediction_of_Massive_Blood_Loss_in_Scoliosis.10.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/spinejournal/Abstract/2013/02150/Prediction_of_Massive_Blood_Loss_in_Scoliosis.10.aspx )

Doctors Decide to Use CT Scans, But With Little Talk of Risks

FRIDAY, March 8 (HealthDay News) -- Most decisions to undergo outpatient computed tomography (CT) scans are made by physicians and risk communication is infrequent, according to a research letter published online March 4 in JAMA Internal Medicine.

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Opioid Guidelines for ER Docs Help, But More Study Needed

FRIDAY, March 8 (HealthDay News) -- Local recommendations like those recently released in New York City aimed at improving opioid prescribing are good first steps but unlikely on their own to address the full problem, according to a viewpoint published in the March 6 issue of the Journal of the American Medical Association.

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Link for Intravaginal Insertion of Products, Bacterial Vaginosis

FRIDAY, March 8 (HealthDay News) -- Intravaginal insertion of over-the-counter products is linked to an increased risk of bacterial vaginosis, according to a study published online March 6 in Obstetrics & Gynecology.

Abstract (http://journals.lww.com/greenjournal/Abstract/publishahead/Intravaginal_Practices_and_Risk_of_Bacterial.99870.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/publishahead/Intravaginal_Practices_and_Risk_of_Bacterial.99870.aspx )

Salty Diet Implicated in Autoimmune Disease

FRIDAY, March 8 (HealthDay News) -- A salty diet could contribute to the development of autoimmune diseases, according to research published in the March 6 issue of Nature.

Abstract 1 (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11868.html )Full Text (subscription or payment may be required) (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11868.html#/access )Abstract 2 (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11981.html )Full Text (subscription or payment may be required) (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11981.html#/access )Abstract 3 (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11984.html )Full Text (subscription or payment may be required) (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11984.html#/access )

Estimated Cost of Diabetes $245 Billion in U.S. in 2012

FRIDAY, March 8 (HealthDay News) -- The economic burden of diabetes was estimated at $245 billion in the United States in 2012, according to a scientific statement published online March 6 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/03/05/dc12-2625.abstract )Full Text (http://care.diabetesjournals.org/content/early/2013/03/05/dc12-2625.full.pdf+html )

Deep Suctioning in Bronchitis Admission Tied to Longer Stays

THURSDAY, March 7 (HealthDay News) -- Deep suctioning used in the first 24 hours after a pediatric admission for bronchitis is associated with increased length of stays (LOS), according to a study published online March 4 in JAMA Pediatrics.

Abstract (http://archpedi.jamanetwork.com/article.aspx?articleid=1659615#Abstract )Full Text (subscription or payment may be required) (http://archpedi.jamanetwork.com/article.aspx?articleid=1659615 )

Sleep Meds Up Hip Fracture Risk Among Nursing Home Residents

THURSDAY, March 7 (HealthDay News) -- There is an increased risk for hip fracture among nursing home residents using a nonbenzodiazepine hypnotic drug, according to a study published online March 4 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1657760#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657760 )Editorial (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657762 )

Deep Brain Stimulation May Be Option in Chronic Anorexia

THURSDAY, March 7 (HealthDay News) -- For patients with chronic, severe, treatment-refractory anorexia nervosa, deep brain stimulation (DBS) seems to be a safe treatment option, according to a phase 1 pilot trial published online March 7 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62188-6/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62188-6/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60057-4/fulltext )

Cochrane Group Skeptical About Latest Roche Pledges

THURSDAY, March 7 (HealthDay News) -- Following requests from Cochrane researchers, Roche has pledged to release full clinical study reports for Tamiflu, although there appear to be conditions attached, according to correspondence published in BMJ.

More Information (http://www.bmj.com/tamiflu/roche )

Coordinated Care Model Suggested for Palliative Care

THURSDAY, March 7 (HealthDay News) -- To deal with the increasing demand for palliative care services, a coordinated palliative care model is proposed, according to a perspective piece published online March 6 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1215620?query=featured_home )

Double-Jointed Adolescents Risk Musculoskeletal Pain

THURSDAY, March 7 (HealthDay News) -- Joint hypermobility (JH) increases the risk of musculoskeletal pain in adolescence, particularly in the shoulder, knee, and ankle/foot, according to a study published online Feb. 28 in Arthritis & Rheumatism.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/art.37836/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/art.37836/pdf )

Self-Monitoring of Blood Glucose Protocol Cuts hs-CRP

THURSDAY, March 7 (HealthDay News) -- Among patients with poorly controlled type 2 diabetes, a structured self-monitoring of blood glucose (SMBG) protocol correlates with reductions in the level of high-sensitivity C-reactive protein (hs-CRP), according to a study published online Feb. 22 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/19/dc12-1711.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/19/dc12-1711.full.pdf+html )

Action Urged to Deal With Handheld Phone Use in Cars

THURSDAY, March 7 (HealthDay News) -- Strong action is urged to tackle the growing problem of handheld phone use and texting while driving, according to a viewpoint published in the March 6 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1660390 )

Insomnia Linked to Greater Risk of Heart Failure

THURSDAY, March 7 (HealthDay News) -- Insomnia is associated with an increased risk of heart failure, with the risk increasing as the number of insomnia symptoms increases, according to a study published online March 5 in the European Heart Journal.

Abstract (http://eurheartj.oxfordjournals.org/content/early/2013/02/28/eurheartj.eht019.short?rss=1 )Full Text (subscription or payment may be required) (http://eurheartj.oxfordjournals.org/content/early/2013/02/28/eurheartj.eht019.full )

Changes Suggested for Hospital Readmission Reduction Program

WEDNESDAY, March 6 (HealthDay News) -- To avoid penalizing hospitals that care for the most vulnerable Americans, modifications are suggested for the Centers for Medicare and Medicaid Services (CMS) Hospital Readmissions Reduction Program (HRRP), according to a perspective piece published online March 6 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1300122?query=featured_home )

White Matter Integrity Varies With MS Cognitive Impairment

WEDNESDAY, March 6 (HealthDay News) -- Diffusion tensor imaging (DTI) metrics reveal distinct white matter (WM) integrity in patients with cognitively preserved (CP) and cognitively impaired (CI) multiple sclerosis (MS), according to research published online March 6 in Neurology.

Abstract (http://www.neurology.org/content/early/2013/03/06/WNL.0b013e31828726cc.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2013/03/06/WNL.0b013e31828726cc.full.pdf+html )

Improving Eating Habits Cuts Depression in Dementia

WEDNESDAY, March 6 (HealthDay News) -- For elderly adults with dementia, symptoms of depression can be improved through nutritional improvement interventions, according to a study published online Feb. 28 in the Journal of Advanced Nursing.

Abstract (http://onlinelibrary.wiley.com/doi/10.1111/jan.12097/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/jan.12097/pdf )

Posttraumatic Stress Disorder Common After Lung Injury

WEDNESDAY, March 6 (HealthDay News) -- Posttraumatic stress disorder (PTSD) symptoms are common in patients recovering from acute lung injury (ALI), according to a study published online March 5 in Psychological Medicine.

Abstract (http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8843288&fulltextType=RA&fileId=S0033291713000214 )Full Text (subscription or payment may be required) (http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8843288&fulltextType=RA&fileId=S0033291713000214 )

Plastics Chemical BPA Tied to Asthma in Inner-City Youth

WEDNESDAY, March 6 (HealthDay News) -- Urinary concentrations of bisphenol A (BPA) are significantly associated with asthma in inner-city children, according to a study published in the March issue of the Journal of Allergy and Clinical Immunology.

Abstract (http://www.jacionline.org/article/S0091-6749(13)00060-2/abstract )Full Text (subscription or payment may be required) (http://www.jacionline.org/article/S0091-6749(13)00060-2/fulltext )

Nonheme Iron Intake Linked to Reduced Risk of PMS

WEDNESDAY, March 6 (HealthDay News) -- Intake of specific minerals seem to be associated with the risk of premenstrual syndrome (PMS), with high intake of nonheme iron linked to reduced risk of PMS, according to research published online Feb. 26 in the American Journal of Epidemiology.

Abstract (http://aje.oxfordjournals.org/content/early/2013/02/23/aje.kws363.abstract )Full Text (subscription or payment may be required) (http://aje.oxfordjournals.org/content/early/2013/02/23/aje.kws363.full.pdf+html )

Symptom-Specific Quality of Life Up in Repeat Sling Procedure

WEDNESDAY, March 6 (HealthDay News) -- Women undergoing repeat midurethral sling procedure have a significantly increased risk of stress urinary incontinence (SUI) failure, but experience greater improvement in urinary symptom-specific quality of life (QOL) than women undergoing a primary procedure, according to research published in the February issue of Obstetrics & Gynecology.

Abstract (http://journals.lww.com/greenjournal/Abstract/2013/02000/Incontinence_Outcomes_in_Women_Undergoing_Primary.10.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/2013/02000/Incontinence_Outcomes_in_Women_Undergoing_Primary.10.aspx )

Most Docs Report Information Overload in EHR-Setting

WEDNESDAY, March 6 (HealthDay News) -- Primary care practitioners (PCPs) using electronic health records (EHRs) are susceptible to information overload and feel that the EHR notification system makes it possible to miss test results, according to a research letter published online March 4 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657753 )

Clinical Trials Published Almost Two Years After Completion

WEDNESDAY, March 6 (HealthDay News) -- Clinical trials are published, on average, almost two years after completion, with time to publication affected by the funding source, number of trial participants, and journal impact factor, according to a research letter published online March 4 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657754 )

Two Drug Classes Found Effective for Restless Legs Syndrome

WEDNESDAY, March 6 (HealthDay News) -- In patients with restless legs syndrome, dopamine agonists and calcium channel alpha-2-delta ligands are effective in reducing symptoms and improving sleep and quality of life, although adverse events are common and often lead to treatment withdrawals, according to a review published online March 4 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1657759#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657759 )

Portable Device May Help Diagnose Vertebrobasilar Stroke

WEDNESDAY, March 6 (HealthDay News) -- A portable device that measures eye movements may help non-specialist physicians diagnose stroke in high-risk patients with acute vertigo or dizziness, according to a study published online March 5 in Stroke.

Abstract (http://stroke.ahajournals.org/content/early/2013/03/05/STROKEAHA.111.000033.abstract )Full Text (subscription or payment may be required) (http://stroke.ahajournals.org/content/early/2013/03/05/STROKEAHA.111.000033.full.pdf+html )

HIV Infection Linked to Risk of Acute Myocardial Infarction

WEDNESDAY, March 6 (HealthDay News) -- HIV infection is associated with an increased risk of acute myocardial infarction (AMI), even after adjustment for Framingham risk factors, according to a study published online March 4 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1659742#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1659742 )Editorial (http://archinte.jamanetwork.com/article.aspx?articleid=1659741 )

Mortality Index Can Accurately Identify 10-Year Mortality Risk

TUESDAY, March 5 (HealthDay News) -- For U.S. adults older than 50 years, a 12-item mortality index can accurately detect 10-year mortality risk, according to a research letter published in the March 6 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1660374 )

Low-Risk Bladder Cancer Rarely Progresses to Muscle Invasion

TUESDAY, March 5 (HealthDay News) -- Low-risk bladder cancer rarely progresses to muscle invasion but is associated with an increased risk of disease-specific mortality compared with matched populations, according to research published in the March issue of The Journal of Urology.

Abstract (http://www.jurology.com/article/S0022-5347(12)04977-4/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)04977-4/fulltext )

Simple Measures Feasible for Promoting Sleep in the ICU

TUESDAY, March 5 (HealthDay News) -- Simple interventions to promote sleep are feasible for patients in medical intensive care units (ICUs) and result in improvements in nighttime noise and reduced incidence of delirium/coma, according to a study published in the March issue of Critical Care Medicine.

Abstract (http://journals.lww.com/ccmjournal/Abstract/2013/03000/The_Effect_of_a_Quality_Improvement_Intervention.12.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/ccmjournal/Abstract/2013/03000/The_Effect_of_a_Quality_Improvement_Intervention.12.aspx )

Atrial Fibrillation Associated With Cognitive Impairment

TUESDAY, March 5 (HealthDay News) -- Atrial fibrillation is strongly associated with a higher risk of cognitive impairment and dementia regardless of stroke history, according to a pooled risk analysis published in the March 5 issue of Annals of Internal Medicine.

Full Text (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1656413 )

Diagnostic Testing Does Little to Reassure Patients

TUESDAY, March 5 (HealthDay News) -- Although further primary care visits may be reduced, diagnostic tests for symptoms with a low risk of serious illness actually do little to reassure patients, decrease their anxiety, or resolve their symptoms over the short or long term, according to research published online Feb. 25 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1656539#Abstract )Full Text (subscription or payment may be required) (http://store.jamanetwork.com/productDetails.aspx?articleid=1656539 )

U.K. Health Performance Worse Than Comparable Countries

TUESDAY, March 5 (HealthDay News) -- The United Kingdom has worse health performance than other comparable countries, according to a study published online March 5 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60355-4/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60355-4/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60188-9/fulltext )

Single Combo Inhaler Beats Standard Rx in Asthma

TUESDAY, March 5 (HealthDay News) -- Maintenance and reliever therapy with a single inhaled corticosteroid plus a rapid-onset, long-acting, β2 agonist (formoterol) seems beneficial for patients with asthma, according to two studies published in the March issue of The Lancet Respiratory Medicine.

Abstract - Papi (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70012-2/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70012-2/fulltext )Abstract - Patel (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70007-9/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70007-9/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70020-1/fulltext )

Blacks Have More Preventable Hypertension Hospitalizations

TUESDAY, March 5 (HealthDay News) -- Blacks have higher rates of preventable hypertension hospitalizations than whites, according to a study published online Feb. 28 in Preventing Chronic Disease.

Full Text (http://www.cdc.gov/pcd/issues/2013/12_0165.htm )

Prospective Human Data Link Mercury Exposure to Diabetes

TUESDAY, March 5 (HealthDay News) -- Young adults exposed to mercury have a higher risk of developing diabetes later in life, according to a study published online Feb. 19 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1842.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/02/14/dc12-1842.full.pdf+html )

Proportion of Black Males in U.S. Medical Schools Dropping

MONDAY, March 4 (HealthDay News) -- The proportion of black males in medical school is decreasing, according to a report published by the Association of American Medical Colleges (AAMC).

More Information (https://www.aamc.org/initiatives/diversity/179816/facts_and_figures.html )

Screening May Reduce Risk for Late-Stage CRC by 70 Percent

MONDAY, March 4 (HealthDay News) -- For average-risk adults, screening colonoscopy is associated with a significant decrease in the risk of any colorectal cancer (CRC) and of right colon cancer; and interventions using electronic health records (EHRs) increase screening rates, according to two studies published in the March 5 issue of the Annals of Internal Medicine.

Full Text - Doubeni (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1656410 )Full Text - Green (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1656409 )

Exercise Tied to Mental Health in Bariatric Sx Candidates

MONDAY, March 4 (HealthDay News) -- Bariatric surgery candidates who meet relatively low thresholds of physical activity are less likely to have recently received treatment for anxiety or depression compared with less active people, according to a study published in the February issue of the Journal of Psychosomatic Research.

Abstract (http://www.jpsychores.com/article/S0022-3999(12)00319-4/abstract )Full Text (subscription or payment may be required) (http://www.jpsychores.com/article/S0022-3999(12)00319-4/fulltext )

Panel Recommends 10 Patient Safety Strategies

MONDAY, March 4 (HealthDay News) -- An expert panel is strongly encouraging the immediate adoption of 10 patient safety strategies and encouraging the adoption of a further 12, according to a supplement published in the March 5 issue of the Annals of Internal Medicine.

Full Text (http://annals.org/article.aspx?articleid=1657884 )Editorial (http://annals.org/article.aspx?articleid=1656416 )

CMS Reports on Progress Toward Improved Health Care

MONDAY, March 4 (HealthDay News) -- Considerable progress has already been made toward improving the quality and delivery of health care, according to a Centers for Medicare and Medicaid Services (CMS) bulletin published online Feb. 28.

More Information (http://content.govdelivery.com/bulletins/gd/USCMS-6e809e )

Computerized Provider Order Entry System Cuts Rx Errors

MONDAY, March 4 (HealthDay News) -- Electronic prescribing through computerized provider order entry (CPOE) systems can substantially reduce medication errors in inpatient acute-care settings, according to a study published online Feb. 20 in the Journal of the American Medical Informatics Association.

Abstract (http://jamia.bmj.com/content/early/2013/01/27/amiajnl-2012-001241.short )Full Text (http://jamia.bmj.com/content/early/2013/01/27/amiajnl-2012-001241.full )

Death of Sibling Boosts Heart Attack Risks for Adults

MONDAY, March 4 (HealthDay News) -- There is an increased risk of death from a myocardial infarction among adults who experience the death of a sibling, according to a study published online Feb. 27 in the Journal of the American Heart Association.

Abstract (http://jaha.ahajournals.org/content/2/2/e000046.abstract )Full Text (subscription or payment may be required) (http://jaha.ahajournals.org/content/2/2/e000046.full )

Childhood ADHD Has Adverse Impact Lasting Into Adulthood

MONDAY, March 4 (HealthDay News) -- Childhood attention-deficit hyperactivity disorder (ADHD) has long-term consequences, with adults at increased risk for death from suicide and having one or more psychiatric disorders other than ADHD, according to a study published online March 4 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2354.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2354.full.pdf+html )

Postpartum Anxiety More Common Than Depression

MONDAY, March 4 (HealthDay News) -- Postpartum anxiety is more common than depression in the days and months following delivery, and is associated with adverse maternal heath outcomes and reduced duration of breastfeeding, according to a study published online March 4 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2147.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2147.full.pdf+html )

Extreme Weather Impacts Ambulance Call-Outs

MONDAY, March 4 (HealthDay News) -- Extreme weather, either hot or cold, significantly affects the number of ambulance call-outs and response times, according to a study published online Feb. 27 in the Emergency Medicine Journal.

Abstract (http://emj.bmj.com/content/early/2013/02/01/emermed-2012-201817.abstract )Full Text (subscription or payment may be required) (http://emj.bmj.com/content/early/2013/02/01/emermed-2012-201817.full )

Delayed Speech Is Not Linked With Autism Stereotypes

MONDAY, March 4 (HealthDay News) -- Children with autism spectrum disorder who are severely language-delayed are more likely to acquire speech and acquire it earlier if they score higher on nonverbal intelligence tests and are less socially impaired, according to a study published online March 4 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2221.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/02/26/peds.2012-2221.full.pdf+html )

Irradiation Shows Lasting Results for Prostate Cancer Control

MONDAY, March 4 (HealthDay News) -- For men with prostate cancer, treatment with irradiation is associated with lasting prostate cancer control, defined as a prostate-specific antigen cutoff of less than 0.2 ng/ml, with no recurrence seen from 15.5 to 25 years, according to a study published in the March issue of The Journal of Urology.

Abstract (http://www.jurology.com/article/S0022-5347(12)05342-6/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)05342-6/fulltext )

Personalized Patient-Risk Info Enhances Informed Choice

FRIDAY, March 1 (HealthDay News) -- When patients are given personalized versus generic risk information, they are better able to make genuinely informed choices about undergoing screening tests, according to research published online Feb. 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001865.pub3/abstract;jsessionid=94CDF1CD396A27209DECE166FF170214.d03t02 )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001865.pub3/full )

Sports, Other Shared Activity Aids Father-Daughter Bonding

FRIDAY, March 1 (HealthDay News) -- For fathers and daughters there is considerable agreement in the events which affect their perception of closeness, with the main turning point being participation in activities together, according to a study published in Human Communication.

Full Text (http://www.uab.edu/Communicationstudies/humancommunication/04_02_Barrett.pdf )

Overused Ophthalmology Tests, Treatments Identified

FRIDAY, March 1 (HealthDay News) -- The American Academy of Ophthalmology (AAO) is participating in the Choosing Wisely campaign and has identified five tests and treatments that may be overused.

More Information (http://www.aao.org/newsroom/release/20130221.cfm )

Patients Increasingly Sue Over Botched Laser Hair Removals

FRIDAY, March 1 (HealthDay News) -- Laser hair removal is the most commonly litigated cutaneous laser surgery procedure, with physicians being named as defendants even when not performing the procedure, according to research published in the February issue of JAMA Dermatology.

Abstract (http://archderm.jamanetwork.com/article.aspx?articleid=1654904#Abstract )Full Text (subscription or payment may be required) (http://archderm.jamanetwork.com/article.aspx?articleid=1654904 )

Sequestration to Impact Health Care-Related Programs

FRIDAY, March 1 (HealthDay News) -- The $85 billion of mandatory cuts in federal spending that take effect March 1 as part of sequestration will be felt across health care and related programs, with cuts to Medicare providers and to the budgets of federal agencies.

More Information (http://www.cms.gov/ )

Young Males With HIV Face Greater Risk of Hearing Loss

FRIDAY, March 1 (HealthDay News) -- HIV infection is significantly associated with an increased risk of developing sudden sensorineural hearing loss (SSHL), according to research published online Feb. 21 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract (http://archotol.jamanetwork.com/article.aspx?articleid=1655348#Abstract )Full Text (subscription or payment may be required) (http://archotol.jamanetwork.com/article.aspx?articleid=1655348 )